After hitting all time high of 21,169 in the first day of March, Dow continued the slide and ended the day with 51 points loss to 20,954. Both S&P 500 and Nasdaq also dropped 0.33% and 0.37% respectively. Winners of the day are all in the biotech sector with shares of TG Therapeutics (TGTX) almost doubled with 90.65% gain to $10.2 per share on successful Phase 3 clinical trials with the company's leukemia treatment drug. Another biotech winner was Concert Pharmaceuticals(CNCE) with shares skyrocketed 62.07% to $15.64 per share as Vertex plans to pay up to $250 million to the company's cystic fibrosis drug.

Shares of BioScrip (BIOS) jumped 23.37% to $2.27 per share on strong 4th quarter report while Aurinia Pharmaceuticals(AUPH) with 11.43% gain as the company announced acceptance of oral presentation of voclosporin at National Kidney Foundation.