Despite Dow losing 112 points to 21,002.97 and Nasdaq sinking 0.73% today, the spotlight goes to IPO blockbuster Snap Inc. (SNAP), gaining 44% to $24.48 on its first day of trading. Other winners, most in the healthcare sector, include Karyopharm Therapeutics (KPTI), surging 25.48% to $13.84 per share on phase 2 study result announcement and Aurinia Pharmaceuticals (AUPH), jumping 22.1% as company clears safety issue of lupus drug.

In the energy sector, shares of Navigator Holdings (NVGS) rose 27.27% to $14 per share as the company's 4th quarter earning beats forcasts while specialty construction chemicals company GCP Applied Technologies (GCP) gained 17.65% despite 4th quarter earning miss